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Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules

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Deposition and atomic power microscopy of person phthalocyanine polymers in between nanofabricated electrodes

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Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of just one wire bridging two electrodes

What distinguishes biology from chemistry is that these parts together make up a residing system. The key of said daily life, I think, lies while in the interactions, the interplay of All those molecules. The big concern concerning the origin of lifetime remains unanswered. How did we ever evolve from basic molecules into your incredibly elaborate methods we see currently? We have no idea. I want to operate on These types of big, open issues.’

2011, 1st in vitro measurements of transport across a single biomimetic nuclear ceesdekker.net pore complex; development of multiplexed magnetic tweezers for kilo-molecule experiments; and fixed the system of homology recognition in DNA homologous recombination

‘You should not just consider the queries of tomorrow, but in addition take into account the inquiries on the day right after tomorrow’

‘The fantastically delicate way through which factors in nature functionality hardly ever ceases to amaze me. If we clear up the puzzle of how daily life came into being, I hope that my amazement for the complexity of development may have amplified and with it my awe for that greatness in the Creator.’

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2001, discovery of one-electron transistors at home temperature based on nanotubes; realization of first logic circuits with carbon nanotube gadgets; and discovery from the molecular construction of DNA restore enzymes with AFM

Visualization of unstained DNA nanostructures with State-of-the-art in-aim transmission electron microscopy methods

Strong-state nanopores have confirmed to become a amazingly flexible probe for single-molecule analysis of DNA. I will explain many of our current results – especially DNA knots – and also our attempts to increase the capabilities of good-point out nanopores even even further, during the way of solitary-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.